The mixed-use schemes, which will be run by the supermarket group's new property unit, involve a variety of residential, office and leisure schemes centred around a new or revamped Sainsbury store.
Chetwood has landed commissions to design a £100m scheme in Brighton, East Sussex, a project in Maidenhead, Berkshire, believed to be worth £40m-50m, a £100m development in Birmingham, and a scheme in High Wycombe, Buckinghamshire, believed to be worth £30m.
Sue Willcox, planning and development manager for property services at Sainsbury, said: "We are taking stores that sit in and around good transport links so that the areas can be regenerated."
The largest Chetwood commission is the £100m Brighton scheme to regenerate a former goods yard for a consortium including the retailer, Railtrack and developer QED.
Urban designer on the 6 ha site is Urbed. Chetwood's design for the 350 housing units, retail space, offices and a health and fitness centre will emphasise sustainability. The scheme is to be built from materials that do not produce carbon emissions and there will be only 20 parking spaces with the residential development. The housing is high density, a key theme of the urban white paper, with 100 dwellings a hectare.
The Brighton project is expected to go to planners next month, with the first phase starting on site in the middle of next year. It is likely to be completed in five years.
The Maidenhead scheme is made up of a 5100 m2 supermarket, a 100-room hotel, office space, leisure and residential uses and a transport hub.
The development will be centred around a public square. The office development is also likely to use natural ventilation.
Chetwood chief executive Laurie Chetwood said of the Maidenhead project: "The office development has got to be a special building as it is on a very prominent site. The local authority is looking on it as an icon."
Planning permission will be requested next spring and work is likely to start on site in the summer. It will take 18 months to build.
Planning applications have already been submitted for the Chetwood schemes in Birmingham and High Wycombe.
A Homebase store, a 6000 m2 Sainsbury, a high-tech business park and apartments are planned for the Selly Oak district of Birmingham.
The High Wycombe project comprises a 3700 m2 supermarket, four retail units, 58 affordable homes, a petrol station and multistorey car parking.
Sainsbury is also planning a £125m scheme in Vauxhall, south London, which will be designed by Hamilton Associates.